α-D-Mannopyranosyl Fluoride

Cas No.2713-54-4 α-D-Mannopyranosyl Fluoride

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Chemical Name: α-D-Mannopyranosyl Fluoride
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2713-54-4
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Molecular Type: C6H11FO5
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Due to the introduction of fluorine atoms, this compound exhibits metabolic characteristics different from natural sugars. For example, fluorine atoms can increase the metabolic stability of drugs, making them more difficult to be degraded by metabolic enzymes in the body, thereby prolonging the half-life of drugs. Therefore, α – D-fluoropyranose mannose can be used in medicinal chemistry to design more stable and efficient glycosylation drugs. In addition, fluoromannose can serve as a modifying group for glycoside drugs. By introducing fluoroglycans, the interaction between drug molecules and targets can be adjusted, thereby optimizing the bioavailability and efficacy of drugs. For example, fluorocarbohydrate drugs typically exhibit good activity in anti-cancer, antiviral, and antibacterial treatments.

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