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Cas No. 98549-88-3 5-Hydroxy-7-azaindole

Cas No. 98549-88-3 5-Hydroxy-7-azaindole

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Chemical Name: 5-Hydroxy-7-azaindole
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98549-88-3
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Molecular Type: C7H6N2O
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1H-pyrrolo [2,3-B] pyridine-5-ol, also known as 5-hydroxy-7azaindole, is a pharmaceutical intermediate. 1H-pyrrolo [2,3-B] pyridine-5-ol can be used to synthesize ABT-199 (Venetoclax). ABT-199 (Venetoclax) is an experimental B-cell lymphoma factor 2 (BCL-2) inhibitor developed jointly by Abbott Laboratories and Roche. BCL-2 is a protein that can prevent apoptosis in some cells, including lymphocytes. ABT-199 aims to selectively inhibit the function of BCL-2 factor, restore the communication system of cells, and allow cancer cells to self destruct, in order to achieve the effect of treating tumors.

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