CAS.98327-87-8 2,2’-Bis(diphenylphosphino)-1,1’-binaphthalene

BINAP, as a ligand, can form catalytic complexes with transition metals (such as ruthenium, rhodium, palladium, etc.) in asymmetric hydrogenation, addition, cyclization and other reactions, greatly improving the enantioselectivity of the reaction. This is crucial for synthesizing drug intermediates with specific chirality, ensuring the biological activity and safety of the final drug. The asymmetric reaction catalyzed by BINAP can precisely introduce one or more chiral centers, which is a crucial step for many biologically active drug molecules. Efficient asymmetric conversion not only improves yield, but also greatly simplifies subsequent separation and purification processes.